Beilstein Arch. 2025, 202551. https://doi.org/10.3762/bxiv.2025.51.v1
Published 18 Aug 2025
The synthesis of allyl-substituted functional aryl compounds is one of the challenges existing in organic chemistry. Herein, we report a method for constructing allyl-substituted aryl boron compounds through nickel-catalyzed reductive allyl-aryl coupling between borylated aryl triflates and allyl alcohols. The method exhibits good substrate applicability under mild conditions. The synthetic utility of the method is highlighted by its gram-scale reaction, modification of complex molecules, and diverse transformation of the products.
Keywords: Nickel, boron, allyl alcohols, cross-coupling, reductive coupling
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Liu, T.; Liu, M.; Han, M.; Xu, G.; Han, H. Beilstein Arch. 2025, 202551. doi:10.3762/bxiv.2025.51.v1
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